Dolenjske Toplice is a settlement and municipality near Novo Mesto in southeastern Slovenia. The town lies on the Sušica River, which joins the Krka 2 km north of town. It is a spa town known for its thermal baths established in 1658 by the Counts of Auersperg.

The parish church in the settlement is dedicated to Saint Anne and belongs to the Roman Catholic Diocese of Novo Mesto. It is a Gothic building that was restyled in the Baroque in the late 17th century.